Granulocytosis

Overview

 * Granulocytosis is defined as the presence of an increased number of granulocytes, a category of white blood cells present in the peripheral blood. Often, the word refers to an increased neutrophil granulocyte count, as neutrophils are the main granulocytes.


 * An increase in eosinophil granulocyte is known as eosinophilia.


 * Granulocytosis can be a feature of a number of diseases:
 * Infection, especially bacterial
 * Malignancy, most notably leukemia (it is the main feature of chronic myelogenous leukemia, CML)
 * Autoimmune disease


 * In cardiovascular disease, increased white blood cell counts have been shown to indicate a worse prognosis.

In alphabetical order

 * Acute intermittent porphyria
 * Acute myeloid leukemia
 * Acute pancreatitis
 * Acute promyelocytic leukemia
 * Adult-onset Still's disease
 * Aminophylline
 * Bronchiolitis obliterans organizing pneumonia
 * Chronic myeloid leukaemia
 * Congenital syphilis
 * Dinoprostone
 * Extrinsic allergic alveolitis
 * Filgrastim
 * Gallbladder empyema
 * Granulocyte colony stimulating factor
 * Granulocyte-macrophage colony stimulating factor
 * Hantavirus
 * Hereditary neutrophilia
 * Hyperimmunoglobulinemia D and periodic fever syndrome
 * Leukocyte adhesion deficiency type 1
 * Leukocyte adhesion deficiency type 2
 * Leukocyte adhesion deficiency type 3
 * Leukemoid reaction
 * Lithium
 * Lymphangitis
 * Mast cell leukemia
 * Polycythaemia rubra vera
 * Recurrent hereditary polyserositis
 * Severe acute respiratory syndrome
 * Splenectomy
 * Sulprostone
 * Urate crystal arthropathy
 * Wegener granulomatosis

Related Chapters

 * Leukocytosis
 * Eosinophilia
 * Monocytosis
 * Lymphocytosis


 * Agranulocytosis
 * Complete blood count