Jump to navigation Jump to search
ICD-10 Q15.0
ICD-9 743.22
DiseasesDB 32591

WikiDoc Resources for Keratoglobus


Most recent articles on Keratoglobus

Most cited articles on Keratoglobus

Review articles on Keratoglobus

Articles on Keratoglobus in N Eng J Med, Lancet, BMJ


Powerpoint slides on Keratoglobus

Images of Keratoglobus

Photos of Keratoglobus

Podcasts & MP3s on Keratoglobus

Videos on Keratoglobus

Evidence Based Medicine

Cochrane Collaboration on Keratoglobus

Bandolier on Keratoglobus

TRIP on Keratoglobus

Clinical Trials

Ongoing Trials on Keratoglobus at Clinical

Trial results on Keratoglobus

Clinical Trials on Keratoglobus at Google

Guidelines / Policies / Govt

US National Guidelines Clearinghouse on Keratoglobus

NICE Guidance on Keratoglobus


FDA on Keratoglobus

CDC on Keratoglobus


Books on Keratoglobus


Keratoglobus in the news

Be alerted to news on Keratoglobus

News trends on Keratoglobus


Blogs on Keratoglobus


Definitions of Keratoglobus

Patient Resources / Community

Patient resources on Keratoglobus

Discussion groups on Keratoglobus

Patient Handouts on Keratoglobus

Directions to Hospitals Treating Keratoglobus

Risk calculators and risk factors for Keratoglobus

Healthcare Provider Resources

Symptoms of Keratoglobus

Causes & Risk Factors for Keratoglobus

Diagnostic studies for Keratoglobus

Treatment of Keratoglobus

Continuing Medical Education (CME)

CME Programs on Keratoglobus


Keratoglobus en Espanol

Keratoglobus en Francais


Keratoglobus in the Marketplace

Patents on Keratoglobus

Experimental / Informatics

List of terms related to Keratoglobus

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Keratoglobus (from Greek: kerato- horn, cornea; and globus round), is a degenerative non-inflammatory disorder of the eye in which structural changes within the cornea cause it to become extremely thin and change to a more globular shape than its normal gradual curve. It causes corneal thinning, primarily at the margins, resulting in a spherical, slightly enlarged eye.


It is a much rarer condition than keratoconus, which is the most common dystrophy of the cornea.[2] Similar to keratoconus it is typically diagnosed in the patient's adolescent years and attains its most severe state in the twenties and thirties.


Keratoglobus is a little-understood disease with an uncertain cause, and its progression following diagnosis is unpredictable. If afflicting both eyes, the deterioration in vision can affect the patient's ability to drive a car or read normal print. It does not however lead to blindness per se.


Keratoglobus continues to be a somewhat mysterious disease, but it can be successfully managed with a variety of clinical and surgical techniques. The patient is at risk for globe perforation because the thinned out cornea is extremely weak.

Surgical treatment

Further progression of the disease usually leads to a need for surgery because of extreme thinning of the cornea. Primarily, large size penetrating keratoplasty has been advocated. Recent additions of techniques specifically for keratoglobus include the "tuck procedure", whereby a 12 mm corneo-scleral donor graft is taken and trimmed at its outer edges. A host pocket is formed at the limbal margin and the donor tissue is "tucked" into the host pocket.

See also

Template:Congenital malformations and deformations of eye, ear, face and neck


Template:WikiDoc Sources